Ndako JA, Nwankiti OO, Olorundare JO, et al. Studies on the serological markers for hepatitis B virus infection among type 2 diabetic patients. J Clin Lab Anal. 2021;35:e23464 10.1002/jcla.23464 [PMC free article] [PubMed] [CrossRef] [Google Scholar]
In immunocompetent humans who have developed anti-HBc and anti-HBs following acute hepatitis B, no transmission of HBV has ever been demonstrated in blood donations[10]. The persistence of virus-specific cytotoxic T lymphocytes as a consequence of stimulation by viral replication and gene expression in this population is necessary to control HBV infection and maintain the long-term persistence of anti-HBc and anti-HBs in these patients[9]. Mild necro-inflammation, even fibrosis, has been observed in patients who have recovered from acute hepatitis B for several years after resolution of hepatitis[11,12].
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